Nuclear and cytoplasmic location of the FER tyrosine kinase.
Open Access
- 1 February 1991
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 11 (2) , 1180-1183
- https://doi.org/10.1128/mcb.11.2.1180
Abstract
The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes.Keywords
This publication has 19 references indexed in Scilit:
- NOVEL PROTEIN-TYROSINE KINASE CDNAS RELATED TO FPS/FES AND EPH CLONED USING ANTI-PHOSPHOTYROSINE ANTIBODY1988
- Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activity.Molecular and Cellular Biology, 1987
- Abelson-transformed fibroblasts contain nuclear phosphotyrosyl-proteins which preferentially bind to murine DNANature, 1987
- Antipeptide antiserum identifies a widely distributed cellular tyrosine kinase related to but distinct from the c-fps/fes-encoded protein.Molecular and Cellular Biology, 1986
- Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products.Molecular and Cellular Biology, 1985
- Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein.Molecular and Cellular Biology, 1985
- Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.Proceedings of the National Academy of Sciences, 1985
- Rapid and Sensitive Protein Similarity SearchesScience, 1985
- The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activityVirology, 1985
- Chapter 3 Preparation of Chromatin from Animal Tissues and Cultured CellsPublished by Elsevier ,1978