The induction of adipose conversion in 3T3‐L1 cells is associated with early phosphorylation of a 60‐kDa nuclear protein

Abstract
The induction of adipose conversion in 3T3‐L1 cells by bezafibrate has been shown to be enhanced by dibutyryl‐cAMP. We here report that the induction of adipose conversion in 3T3‐L1 cells, by either bezafibrate and dibutyryl cAMP, or isobutylmethyxanthine alone, is associated with a very early phosphorylation of a 60‐kDa acidic protein found in the nuclear fraction.