Studies on the morphogenesis ofCandida albicans
- 1 January 1965
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 4 (2) , 126-130
- https://doi.org/10.1080/00362176685190291
Abstract
It was shown that pseudo-germ tubes of Candida albicans were formed when blastospores were introduced into aqueous extracts of exsanguinated rabbit organs. The percentage of cells forming pseudo-germ tubes and their subsequent growth was greatest in extracts from brain and kidney. They were formed to a lesser extent in extracts of liver, heart, spleen and lungs. It is considered that the known renal predilection of C. albicans may be attributable in part to the ability of kidney extract, in the absence of humoral factors, to induce rapid production of the tissue phase. On montre que des pseudo tubes germinatifs de C. albicans sont formés quand des blastospores sont introduits dans des extraits aqueux d'organes de lapins saignés à blanc. Le pourcentage des cellules qui forment ces pseudo tubes germinatifs et qui donnent une croissance ultérieure est plus élevé dans des extraits de cerveau et de rein. Les pseudo tubes sont formés à un moindre degré dans les extraits de foie, coeur, rate et poumon. On considère que la prédilection bien connue de C. albicans pour le rein peut être au moins partiellement, attribuable au fait que les extraits de rein, exempts de facteurs humoraux, induisent la production rapide de la phase tissulaire.Keywords
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