The Acylation of β-Keto Ester Dianions
- 15 April 1974
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 52 (8) , 1343-1351
- https://doi.org/10.1139/v74-205
Abstract
A method for the successful acylation of the dianion of simple β-keto esters to yield β,δ-diketo esters has been developed. The dianion of methyl acetoacetate also reacts with the monoanion of methyl acetoacetate to give a triketo ester which cyclizes to methyl orsellinate. These dianions also add to nitriles to give 5-amino-3-keto-4-pentenoates which may in some cases cyclize to 4-hydroxypyridones.Keywords
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