Abstract
The metabolism of oestrone, oestradiol-17α and oestradiol-17β has been studied in rabbit liver slices. Oestradiol-17α and oestradiol-17β were isolated as metabolites of oestrone. When oestradiol-17α17α was incubated oestrone and oestradiol-17β were formed, whereas oestradiol-17β gave rise to oestradiol-17α and oestrone. Quantitative experiments showed that after incubation of oestrone 5–8 times as much oestradiol-17β was found as oestradiol-17α.

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