The Conversion of Carboxylic Acids into Amides via NCS/Triphenylphosphine
- 1 April 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (7) , 959-968
- https://doi.org/10.1080/00397919508012657
Abstract
Amides can be generated in very high yields under mild conditions from the corresponding carboxylic acid and amine in the presence of equivalent amounts of triphenylphosphine and N-halosuccinimides, e.g., NCS or NBS.Keywords
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