Zinc distribution disorder in psoriasis
- 1 January 1977
- journal article
- conference paper
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 259 (1) , 97-100
- https://doi.org/10.1007/bf00562742
Abstract
In 64 patients with psoriasis and in 54 persons without any skin disease the amount of zinc was estimated in plasma and in the erythrocytes using atomic absorption spectrophotometry. The findings showed an elevated plasma level and a lower zinc content of blood erythrocytes in psoriasis. Both values were statistically significant. No relation was found between these changes and the percentage skin surface covered by psoriatic lesions. The disturbed distribution of zinc in psoriasis may be due to disturbances of histidine metabolism or to changes of the permeability of the cell membranes associated with this skin disease. An 64 Psoriatiker fand sich eine statistisch signifikante Erhöhung des Zinkspiegels im Plasma und eine ebenfalls statistisch signifikante Minderung des Zinkgehalts in den Bluterythrocyten, verglichen mit 54 gesunden Personen. Die erhobenen Befunde zeigten keine Relation zur Ausdehnung der Hautkrankheit. Die Verteilungsstörung dieses Spurenelements bei Psoriasis könnte auf eine Störung des Histidin-Stoffwechsels oder auf Veränderungen der Erythrocytenmembran beruhen.This publication has 30 references indexed in Scilit:
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