Brain pH in Migraine: An In Vivo Phosphorus-31 Magnetic Resonance Spectroscopy Study
- 1 December 1988
- journal article
- research article
- Published by SAGE Publications in Cephalalgia
- Vol. 8 (4) , 273-277
- https://doi.org/10.1046/j.1468-2982.1988.0804273.x
Abstract
The intracellular pH (pHi) of cerebral cortex was measured in migraine patients by use of in vivo phosphorus-31 NMR spectroscopy. No changes in pHi were measured during a migraine attack. The long-standing concept that the headache of migraine is due to cerebral vaso-dilatation induced by prodromal vasospasm-induced ischemic acidosis is not substantiated.Keywords
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