Human chorionic gonadotropin. IV. Synthesis of a hexadecapeptide corresponding to the C-terminal sequence 130-145 of the .BETA.-subunit of human chorionic gonadotropin (hCG).
- 1 January 1980
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 28 (9) , 2707-2713
- https://doi.org/10.1248/cpb.28.2707
Abstract
The hexadecapeptide corresponding to sequence 130-145 of the β-subunit of human chorionic gonadotropin (hCG) according to the amino acid sequence proposed by Morgan et al. was synthesized by successive azide condensation of 4 peptide fragments, followed by TFA treatment and catalytic hydrogenation. This peptide was conjugated with bovine serum albumin (BSA). Antiserum produced against this conjugate did not bind with 125I-hCG.Keywords
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