Report to the Secretary of HEW From the Medical Advisory Group on Cyclamates

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Abstract
The Medical Advisory Group on Cyclamates appointed by Secretary Finch met on Nov 17 and 18, 1969, with representatives of the Food and Drug Administration and the National Institutes of Health to review the currently available data on the possible harmful effects of these nonnutritive sweeteners in relation to their potential benefits. The group considered the data on carcinogenic, mutagenic, teratogenic, enzymatic, osmotic, and growth effects of cyclamates and on their possible adverse influence in interaction with other drugs. After carefully reviewing the evidence currently available, the Medical Advisory Group on Cyclamates unanimously supported the secretary's prohibition of the inclusion of cyclamates in beverages for general use, and in the future processing of general purpose foods and vegetables. It recognized, however, that in the medical management of individuals with diabetes (and particularly in the case of juvenile diabetes) or patients in whom weight reduction and control are essential for health,

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