Structure of the DNA binding domain of E. coli SSB bound to ssDNA.
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- 1 August 2000
- journal article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 7 (8) , 648-652
- https://doi.org/10.1038/77943
Abstract
The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coli (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 A. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.Keywords
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