Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells.
Open Access
- 31 January 1982
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 155 (2) , 611-616
- https://doi.org/10.1084/jem.155.2.611
Abstract
A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti-idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule.This publication has 21 references indexed in Scilit:
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