Jejunal mucosal gamma glutamyl transferase activity in coeliac disease.
Open Access
- 1 June 1977
- Vol. 18 (6) , 484-487
- https://doi.org/10.1136/gut.18.6.484
Abstract
In view of data suggesting that deficiency of gamma glutamyl transferase (GGT) may be the primary abnormality in the small-intestinal mucosa of patients with coeliac disease, this enzyme was measured in mucosal biopsies from coeliac patients at different stages of treatment. Activity was only slightly reduced in only one of nine well-treated patients, suggesting that deficiency of this enzyme has no primary role in the aetiology of coeliac disease.This publication has 14 references indexed in Scilit:
- The Expression of Enzyme Activity of Biopsy Tissue from the Small IntestineDigestion, 1977
- γ‐glutamyltranspeptidase in intestinal brush border membranesFEBS Letters, 1975
- Intestinal Dipeptidases and Disaccharidases in Celiac Disease in AdultsGastroenterology, 1970
- Intestinal DipeptidasesScandinavian Journal of Gastroenterology, 1968
- Demonstration of γ-glutamyl transpeptidase activity in human jejunal mucosaClinica Chimica Acta; International Journal of Clinical Chemistry, 1967
- Jejunal disaccharidases and some observations on the cause of lactase deficiency.BMJ, 1966
- A Clinical and Histochemical Study of Celiac Disease Before and During a Gluten-Free DietGastroenterology, 1965
- Functional histochemistry of the small bowel mucosa in malabsorptive syndromesGut, 1964
- Method for assay of intestinal disaccharidasesAnalytical Biochemistry, 1964
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951