Potential allogeneic graft-versus-tumor effect in a patient with ovarian cancer
- 1 March 2000
- journal article
- case report
- Published by Springer Nature in Bone Marrow Transplantation
- Vol. 25 (6) , 681-682
- https://doi.org/10.1038/sj.bmt.1702206
Abstract
A 33-year-old woman developed progressive ovarian cancer resistant to classical chemotherapy agents. We performed a bone marrow allograft after a myeloablative regimen. During hematological recovery, she developed acute graft-versus-host disease (GVHD). From this time her tumor diminished progressively. One year post transplant she has limited chronic liver GVHD and is still free of disease. The complete remission of advanced ovarian cancer was probably related to the GVHD which might therefore provide a new treatment option for this disease. Bone Marrow Transplantation (2000) 25, 681–682.Keywords
This publication has 5 references indexed in Scilit:
- Successful Treatment of Metastatic Renal Cell Carcinoma With a Nonmyeloablative Allogeneic Peripheral-Blood Progenitor-Cell Transplant: Evidence for a Graft-Versus-Tumor EffectJournal of Clinical Oncology, 1999
- Allogeneic peripheral-blood progenitor-cell transplantation for poor-risk patients with metastatic breast cancer.Journal of Clinical Oncology, 1998
- Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic DiseasesBlood, 1998
- High-dose chemotherapy with hematopoietic rescue in patients with stage III to IV ovarian cancer: long-term results.Journal of Clinical Oncology, 1997
- Graft-versus-tumour and graft-versus-leukaemia effect in patient with concurrent breast cancer and acute myelocytic leukaemiaThe Lancet, 1996