β-Globin Gene Haplotypes in Polynesians Are Predominantly Southern Chinese in Type
- 1 January 1990
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 40 (5) , 285-289
- https://doi.org/10.1159/000153946
Abstract
.beta.-Globin gene haplotypes obtained in Polynesian Samoans were similar to those decribed in Southern Chinese. An atypical HindIII restriction fragment length polymorphism detected with pRK29, a 3'' .beta.-globin gene probe, was present at a gene frequency of 7% in Samoans. Haplotype patterns suggest that this polymorphism may have arisen by 1 or 2 mutational events. DNA haplotypes derived from the .beta.-globin gene cluster confirm nuclear and mitochondrial DNA data that Polynesian precursor populations were East Asian in origin.Keywords
This publication has 1 reference indexed in Scilit:
- Meiotic recombination between two polymorphic restriction sites within the beta globin gene cluster.Journal of Medical Genetics, 1986