Behavioral Changes in Rats following Bufotenine Injection

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Abstract
A time sampling procedure was used to observe the behavioral effects of IP bufotenine injection in the rat. The results indicated an attenuation of locomotor activity which varied directly as a function of drug dosage. In addition, all response components typically associated with a general activity pattern were selectively affected by bufotenine. Interpretation of the response decrement in terms of a generalized motor loss was not supported by other aspects of the data. Evidence suggesting that behavioral changes following bufotenine treatment are due to a disruption of sensory processes was discussed.