The reduction in fitness from genetic drift at heterotic loci in small populations
- 1 February 1970
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 15 (2) , 257-259
- https://doi.org/10.1017/s0016672300001580
Abstract
SUMMARY: In finite populations, loci maintained segregating by hétérozygote superiority will be disturbed from their equilibrium positions by genetic sampling and the mean fitness of individuals will consequently be reduced. A general expression for this reduction is obtained for the segregation of two alleles. If the probability of continued segregation at the locus is high, the reduction tends to 1/4N, irrespective of the strength of selection, whereNis the effective population size. This will always be much less than the segregation load. Ifnalleles are segregating, so that all heterozygotes have the same fitness, the reduction tends to (n−1)/4N.Keywords
This publication has 1 reference indexed in Scilit:
- ISOLATION BY DISTANCEGenetics, 1943