The production of a human monoclonal antibody defining a split of HLA‐DRw13 (DRw13b)

1 September 1990

journal article
research article
Published by Wiley in Tissue Antigens

Vol. 36 (3) , 100-102
https://doi.org/10.1111/j.1399-0039.1990.tb01808.x

Abstract

By use of the heterohybridoma technique we have produced a human monoclonal antobody (NDS40) which detects a split of HLA-DRw13 (DRw13b) which is in linkage with HLA-DQw1. In addition, the antibody reacts with cells positive for HLA-DRw8 and DRw11, but does not react with the commonly found split of DRw13 (DRw13a) which is associated with DQwl. NDS40 is cytotoxic and is of the lambda IgM class.

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