Substance P injected into the region of the nucleus basalis magnocellularis facilitates performance of an inhibitory avoidance task
- 1 September 1986
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 90 (2) , 281-283
- https://doi.org/10.1007/bf00181260
Abstract
The neuropeptide substance P (SP) was injected into the region of the nucleus basalis magnocellularis (NBM). The influence of SP on the performance of the single trial “uphill avoidance task” was tested. The post-trial injection of 1 ng SP (in 0.5 μl volume) led to significantly longer latencies in the uphill response. This result can be interpreted in terms of a facilitating effect of SP on performance of an inhibitory avoidance response.Keywords
This publication has 13 references indexed in Scilit:
- Avoidance learning in rats devoid of the telencephalon plus thalamusBehavioural Brain Research, 1985
- Behavioral investigation of the coexistence of substance P, corticotropin releasing factor, and acetylcholinesterase in lateral dorsal tegmental neurons projecting to the medial frontal cortex of the ratPeptides, 1985
- Central action of substance P: Possible role in rewardBehavioral and Neural Biology, 1985
- Evidence for a projection from the lateral preoptic area and substantia innominata to the ‘mesencephalic locomotor region’ in the ratBrain Research, 1984
- Substance P in the ascending cholinergic reticular systemNature, 1983
- The Cholinergic Hypothesis of Geriatric Memory DysfunctionScience, 1982
- Facilitation of learning by post-trial injection of substance P into the medial septal nucleusBehavioural Brain Research, 1980
- Post-trial injection of substance P into lateral hypothalamus and amygdala, respectively, facilitates and impairs learningBehavioral and Neural Biology, 1979
- Differential effects on learning by ventromedial vs lateral hypothalamic posttrial injection of substance PPharmacology Biochemistry and Behavior, 1979
- Retrograde amnesia produced by post-trial injection of substance P into substantia nigraBrain Research, 1978