Time trends (1980–1987) of ten selected informative morphogenetic variants in a newborn population

1 July 1990

journal article
research article
Published by Wiley in Clinical Genetics

Vol. 38 (1) , 33-37
https://doi.org/10.1111/j.1399-0004.1990.tb03544.x

Abstract

The annual prevalence rates of ten selected informative morphogenetic variants (IMVs) were studied in 31 194 newborn infants over a period of 8 years (1980–1987). Two of them (preauricular sinus and ocular hypertelorism) revealed a highly significant decrease by logistic regression analysis. The other eight presented a stable pattern or small fluctuations which did not reach statistical significance. These data may serve as valuable baseline rates for monitoring IMVs in a specific newborn population. Their potential informative value as indicators of altered morphogenesis and their power for monitoring programs of environmental teratogenicity should be carefully verified.

Keywords

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