GASTRIC ACIDITY FOLLOWING PARTIAL GASTRECTOMY AND VAGOTOMY

Publisher Website
Google Scholar
Abstract
Following partial gastrectomy and complete vagotomy there is profound decrease in acid secretion in response to a Liebig''s extract test meal which is greater than after partial gastrectomy alone. In 51 expts. on 4 dogs, 17 were characterized by an-acidity. Histamine caused a marked secretion of acid. The intestinal phase of acid secretion was very marked and unusually prolonged. Following operation the gastric samples contained large amts. of a viscid mucus. In anacidity mucus was abundant but it was usually not in evidence when large amts. of acid were being secreted in response to histamine and in the intestinal phase. This suggests that the mucus is the result and not the cause of the lowered acidity. The average acidity of the gastric contents of each of the 4 dogs was below the threshold value of acid necessary for the digestion of living tissues as detd. by Dragstedt.

This publication has 4 references indexed in Scilit: