Diazotizable arylamine cellulose papers for the coupling and hybridization of nucleic acids
Open Access
- 11 March 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (5) , 1799-1810
- https://doi.org/10.1093/nar/10.5.1799
Abstract
We describe the synthesis of a family of arylamine-substituted papers which can be diazotized and coupled with nucleic acids. The synthesis is simple and uses readily obtainable starting materials. A partial characterization of the nucleic acid binding activity is reported, as well as a demonstration of the utility of the activated paper for the detection of electrophoretically separated RNA by blot transfer and hybridization.Keywords
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