Total synthesis of a nuclear analogue of the penicillin–cephalosporin antibiotics
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 15,p. 865-867
- https://doi.org/10.1039/c29710000865
Abstract
A synthetic route has been developed for the preparation of nuclear analogues of the penicillin–cephalosporin group of antibiotics and is illustrated by the synthesis of (2R,6R,7S)-8-oxo-7-phenylacetamido-1-azabicyclo[4,2,0]octane-2-carboxylic acid (17) from D-pipecolic acid.Keywords
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