Optical Resolution of Pantolactone by Inclusion Crystallization with (R,R)-(−)-trans-2,3-Bis(diphenylhydroxymethyl)-1,4-dioxaspiro[4.5]decane, and Crystal Structure of the Resulting 1:1 Complex

Abstract
Pantolactone was resolved very efficiently by complex formation of its (S)-(−) isomer with the title host compound. The structure of the 1:1 complex was elucidated by X-ray crystallography.