Immunoglobulin allotyping (Gm, Km) of GAW5 families

1 January 1989

journal article
research article
Published by Wiley in Genetic Epidemiology

Vol. 6 (1) , 31-33
https://doi.org/10.1002/gepi.1370060108

Abstract

The following Gm and Km immunoglobulin allotypes were determined on the Genetic Analysis Workshop 5 insulin-dependent diabetes mellitus (GAW5 IDDM) families: Glm (1,2,3,17), G2m (23), G3m (5,10,11,13,14,21,28) and Km (1,3). Since the allotype G2m (23) has been rarely studied, due to paucity of typing reagents, it was of interest to compare the frequency of the halotype encoding this allotype in parents of North American GAW5 IDDM families with the frequency found in a previous investigation of healthy North Americans. Results indicated very similar frequencies of Gm haplotypes in the two groups.

Keywords

This publication has 2 references indexed in Scilit:

A Gm Haplotype Study in Relation with HLA-DR in 155 Insulin-Dependent Diabetic Patients and Their Affected and Non Affected Siblings
Experimental and Clinical Endocrinology & Diabetes, 1987
INTERACTIVE EFFECT OF GENES ASSOCIATED WITH IMMUNOGLOBULIN ALLOTYPES AND HLA SPECIFICITIES ON SUSCEPTIBILITY TO HAEMOPHILUS INFLUENZAE DISEASE
International Journal of Immunogenetics, 1984