Direct current cardioversion. Effect on creatine kinase, lactic dehydrogenase and myocardial isoenzymes

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Abstract
Creatine kinase (CK), lactic dehydrogenase (LDH) and their isoenzyme determinations (CK-MB [myocardial] and LDH1) were useful adjuncts in verification of myocardial injury. To determine whether DC cardioversion affects these serum enzyme levels total CK, total LDH, CK-MB and LDH1 levels were recorded serially during 24 h following elective DC cardioversion in 18 patients without cardiac ischemia. New postcardioversion elevations in total CK and total LDH levels were small and occasional: CK (1 of 18 patients), LDH (4 of 18 patients). Elevations of CK-MB or LDH1 following cardioversion did not develop in any patients. New CK-MB or LDH1 elevations associated with arrhythmias must result from myocardial damage unrelated to DC cardioversion.

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