Plasma Cortisol Response to Dexamethasone Suppression in Depressed and Control Patients
- 1 April 1971
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 24 (4) , 320-326
- https://doi.org/10.1001/archpsyc.1971.01750100030004
Abstract
Adrenocortical overactivity as a theory in the pathogenesis of depression cannot be supported on the basis of this study. Plasma cortisol response to dexamethasone was normal in both bipolar and unipolar depressives, reactive depressives and schizophrenics. As a group, schizophrenics showed significantly higher morning cortisol values than the depressed population.Keywords
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