Subclinical Thyroid Disease
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Open Access
- 14 January 2004
- journal article
- review article
- Published by American Medical Association (AMA) in JAMA
- Vol. 291 (2) , 228-238
- https://doi.org/10.1001/jama.291.2.228
Abstract
Subclinical or "mild" thyroid disease is a common disorder, particularly in middle-aged and elderly individuals.1 Greater sensitivity of assays and more frequent assessment of serum thyroid-stimulating hormone (TSH) levels have resulted in more patients requiring interpretation of abnormal thyroid function test results. However, controversy surrounds the definition, clinical importance, and necessity for prompt diagnosis and treatment of subclinical thyroid disease. Previous review articles2-6 and position statements7,8 differ in their conclusions and recommendations, often a consequence of difficulties in interpreting inadequate and conflicting data. In the midst of this uncertainty, clinicians still desire expert guidance for the diagnosis and management of subclinical thyroid disease.Keywords
This publication has 2 references indexed in Scilit:
- Low Serum Thyrotropin (Thyroid Stimulating Hormone) in Older Persons without HyperthyroidismThe Endocrinologist, 1992
- Heterophilic Serum Antibodies: A Cause for Falsely Elevated Serum Thyrotropin LevelsMayo Clinic Proceedings, 1987