Chemical Synthesis of Fully and Partially Xyloadenosine-Substituted 2′, 5′-Oligoadenylates Designed as New Potential Antiviral and Antitumor Agents
- 1 July 1986
- journal article
- review article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 5 (3) , 275-300
- https://doi.org/10.1080/07328318608069978
Abstract
Seven 2′, 5′-oligoadenylate analogues containing 9-β-D-xylofuranosyladenine (xyloaadenosine, XyloA) at the 2′-end or at other positions were synthesized by the phosphotriester method. These new analogues, from dimer to tetramers, exhibit antiproliferative activity which is probably due to their degradation to xyloadenosine units.This publication has 106 references indexed in Scilit:
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