Radiosensitivity of Mammalian Cells, VII. Aggregation and Pseudo-glomerule Formation of Dissociated Kidney Cells from Irradiated New Born Mice

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Abstract
The effects of irradiation on aggregate and pseudo-glomerule forming activity were studied quantitatively using dissociated kidney cells from new born mice. The dissociated cells formed macroscopic aggregates and microscopic inner structures, pseudo-glom erules, on the bottom of plastic dishes. The inhibitory effects of irradiation on aggregation and pseudo-glomerule formation were detectable with a dose of as low as 10 R. However these abilities to form aggregates or pseudoglomerules were not completely lost even after irradiation with a dose of 1000R.