Abstract
UDP-d-glucuronic acid (UDP-GlcA) is a key intermediate in the synthesis of other UDP-sugars and also an important glucuronosyl donor for cell wall polysaccharide synthesis. UDP-GlcA can be synthesised via two routes in plants: the myo-inositol oxidation pathway and a pathway involving UDP-glucose dehydrogenase (UDPGDH)-catalysed oxidation of UDP-glucose (UDP-Glc). This review discusses the synthesis of UDPGlcA within the context of cell wall biosynthesis.