Increased oxidative stress in the RAW 264.7 macrophage cell line is partially mediated via the S‐nitrosothiol‐induced inhibition of glutathione reductase
Open Access
- 26 February 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 445 (2-3) , 274-278
- https://doi.org/10.1016/s0014-5793(99)00139-8
Abstract
We investigated whether endogenously or exogenously produced nitric oxide (NO) can inhibit cellular glutathione reductase (GR) via the formation of S‐nitrosothiols to decrease cellular glutathione (G...Keywords
This publication has 26 references indexed in Scilit:
- Glutathione Regulates Nitric Oxide Synthase in Cultured HepatocytesAnnals of Surgery, 1997
- No-induced oxidative stress and glutathione metabolism in rodent and human cellsFree Radical Biology & Medicine, 1996
- Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathioneFree Radical Biology & Medicine, 1996
- Glutathione antioxidant system as a marker of oxidative stress in chronic renal failureFree Radical Biology & Medicine, 1996
- Inhibition of Human Glutathione Reductase by S‐nitrosoglutathioneEuropean Journal of Biochemistry, 1995
- Nitric Oxide Generation during Cellular Metabolization of the Diabetogenic N-Mefhyl-N-Nitroso-Urea Streptozotozin Contributes to Islet Cell DNA DamageBiological Chemistry Hoppe-Seyler, 1995
- Redox signaling: Nitrosylation and related target interactions of nitric oxideCell, 1994
- The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.The Journal of Experimental Medicine, 1994
- Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginineBiochemical and Biophysical Research Communications, 1992
- FAD and GSH participate in macrophage synthesis of nitric oxideBiochemical and Biophysical Research Communications, 1990