Amplitude Histography of the EEG in Psychopharmacological Research
- 20 January 1979
- journal article
- research article
- Published by Georg Thieme Verlag KG in Pharmacopsychiatry
- Vol. 12 (01) , 94-101
- https://doi.org/10.1055/s-0028-1094599
Abstract
The amplitude histography is applied in a quantitative EEG-study of drug-effects in the isolated perfused rat brain; parallel to this, the EEG is analyzed by a frequency-orientated technique (interval histography). Chlorpromazine and 5 of its metabolites, as well as imipramine and imipramine-NO are investigated with the aim of differentiating the central drug effects by means of the EEG. Results Die Amplitudenhistographie wurde in einer quantitativen EEG-Studie über Pharmakawirkungen am isoliert perfundierten Rattenhirn angewandt; daneben wurden Intervallhistogramme ausgewertet. Chlorpromazin und 5 seiner Metaboliten sowie Imipramin und Imipramin-NO wurden hinsichtlich ihrer EEG-Effekte untersucht. ErgebnisseKeywords
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