Divergent Biological Effects of Adenosine and Dibutyryl Adenosine 3′,5′-Monophosphate on the Isolated Fat Cell
- 24 July 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 169 (3943) , 387-388
- https://doi.org/10.1126/science.169.3943.387
Abstract
Adenosine 3′,5′-monophosphate stimulated production of carbon dioxide and lipid from glucose, whereas its dibutyryl derivative inhibited this conversion. Addition of the dibutyryl derivative to the isolated fat cell further stimulated lipolysis induced by adrenocorticotropic hormone, whereas addition of adenosine 3′,5′-monophosphate inhibited this lipolysis. Hence, measured by these two parameters, the biologic properties of adenosine 3′,5′-monophosphate and its dibutyryl derivative are distinctly different.Keywords
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