[Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)].

  • 16 May 1975
    • journal article
    • Vol. 100  (20) , 1135-8
Abstract
Somatostatin (200 mug/h) was administered to five healthy volunteers after submaximal stimulation of exocrine pancreatic secretion with 0.33 KU secretin or cholecystokinin-pancreozymin, given intravenously. In all instances there was a significant reduction in duodenal secretory volume after secretin, without any change in HCO3- concentration. Stimulation of enzyme secretion by cholecystokinin-pancreozymin was significantly inhibited and gallbladder contraction abolished.

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