Some Substituted Pyruvic Acid (Phthalazin‐1‐yl)hydrazones and [1,2,4]Triazinophthalazines as Possible Antimicrobial and Antineoplastic Agents
- 1 January 1981
- journal article
- research article
- Published by Wiley in Archiv der Pharmazie
- Vol. 314 (12) , 1030-1034
- https://doi.org/10.1002/ardp.19813141209
Abstract
In search for novel antimicrobial and antineoplastic agents, the synthesis of some substituted arylidenepyruvic acid (phthalazin‐l‐yl)hydrazones 3 and their cyclodehydration to 3‐substituted 4H‐[1,2,4]triazino[3,4‐α] phthalazin‐4‐ones 4 is reported. Compounds 4a, 4b and 7 were screened for in vitro antibacterial and antifungal activities and were inactive.This publication has 6 references indexed in Scilit:
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