The antigenic activity of some poliomyelitis vaccines used in the United Kingdom in 1958
- 1 December 1960
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 58 (4) , 399-408
- https://doi.org/10.1017/s0022172400038547
Abstract
The potency in man of eight different commercial vaccines and an experimental vaccine, as judged by the antibody response after the primary course of two injections and after a booster dose 9–12 months later, was compared. All the vaccines produced good responses to Types 2 and 3 but some were less satisfactory for Type 1. The relation of potency to protection in man is discussed and the use of one of the vaccines as a minimum standard for this country is suggested.Keywords
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