Die Wirkung von Streptomycin, Aureomycin undmeso-Inosit auf die Lipoide der Rattenleber

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Abstract
Streptomycin and Aureomycin were used to eliminate the bacterial flora in the gut of white rats, to test whether inositol is provided by the micro-organisms. The biological activity of inositol which was used as an index was its lipotropic action. An estimate of the absence or presence of this lipotropic action was obtained by measuring changes in liver phosphatide and free fat content. With a normal diet, Aureomycin had an anti-lipotropic effect, which was not relieved by inositol. The effect of streptomycin was smaller. Using a diet lacking in lipotropic factors, streptomycin had a strong anti-lipotropic effect. This was completely reversed by inositol. Lipotropic factors not identical with inositol may be involved.