Influence of ionic and non-ionic radiographic contrast media on the vasomotor tone of epicardial coronary arteries
- 1 November 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in European Heart Journal
- Vol. 10 (suppl F) , 60-65
- https://doi.org/10.1093/eurheartj/10.suppl_f.60
Abstract
The effect of ionic and non-ionic contrast media on the vasomotility of epicardial coronary arteries was investigated in 21 patients during coronary angiography by use of either diatrizoate-76% (10 patients, group A) or iopromide-370 (11 patients, group B). Coronary angiograms were taken in RAO 30° projection before (=reference) and directly after (t0) diagnostic angiography of the left coronary artery (approx. 7 dye injections in approx. 7 min). Additional angiograms in the same projection followed after 1, 3, 6 and 10 min. Mean diameters of angiographically normal coronary segments were analysed with an automatic edge detection system (CAAS). With diatrizoate-76% coronary dilation at t0 averaged 18·9±6·7% (P−1), and negatively (P0 (mean interval 73±35s). Coronary dilation was unchanged 1 min after t0 (18·3±5·4%, P0 was mild (5·4±4·3%; P3 min should be observed.Keywords
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