Dynamically Modified Capillary Columns for Liquid Chromatographic Separations of Biological Compounds
- 1 September 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 23 (9) , 381-384
- https://doi.org/10.1093/chromsci/23.9.381
Abstract
Dynamically modified open tubular capillary columns were evaluated for separations of biological and clinical interest. Small diameter, dynamically modified columns were readily prepared by simple addition of cetyltrimethylammonium salts to the mobile phase. Separations similar to those obtained on conventional reversed-phase columns were observed for neutral solutes, and ion-pair reversed-phase separations were observed for charged solutes. Borosilicate and standard flint glasses were evaluated with respect to common etching procedures. A potential clinical application is presented in the separation of antitumor drugs.This publication has 1 reference indexed in Scilit:
- Studies of open tubular micro capillary liquid chromatography. 1. The development of open tubular micro capillary liquid chromatographyJournal of High Resolution Chromatography, 1978