FluBlok, a recombinant hemagglutinin influenza vaccine

Open Access

1 November 2008

journal article
research article
Published by Wiley in Influenza and Other Respiratory Viruses

Vol. 2 (6) , 211-219
https://doi.org/10.1111/j.1750-2659.2008.00053.x

Abstract

FluBlok, a recombinant trivalent hemagglutinin (HA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive alternative to the current egg-based trivalent inactivated influenza vaccine (TIV) manufacturing process. FluBlok contains three times more HA than TIV and does not contain egg-protein or preservatives. This review discusses the four main clinical studies that were used to support licensure of FluBlok under the 'Accelerated Approval' mechanism in the United States.

Keywords

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