Increases in Fluoride, Calcium, and Phosphate in Dental Plaque Resulting from the Use of a Mineralizing Mouthrinse Containing Urea and Monofluorophosphate

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Abstract
A mouthrinse used ten times over a four-day period increased the concentration of acid-extractable fluoride in immature plaque by 320%, calcium by 190%, and phosphate by 97%. Corresponding increases in mature plaque were smaller, yet significant. Diffusion of the ions from plaque was restricted, and hence a prolonged caries-inhibitory effect can be expected.