Insulin action and type 2 diabetes: lessons from knockout mice
- 1 April 1999
- journal article
- Published by Wolters Kluwer Health in Current Opinion in Endocrinology, Diabetes and Obesity
- Vol. 6 (2) , 141-145
- https://doi.org/10.1097/00060793-199904000-00010
Abstract
No abstract availableThis publication has 17 references indexed in Scilit:
- Phosphoinositide 3-kinase: the key switch mechanism in insulin signallingBiochemical Journal, 1998
- Evidence That IRS-2 Phosphorylation Is Required for Insulin Action in HepatocytesJournal of Biological Chemistry, 1998
- Disruption of IRS-2 causes type 2 diabetes in miceNature, 1998
- A Novel 160-kDa Phosphotyrosine Protein in Insulin-treated Embryonic Kidney Cells Is a New Member of the Insulin Receptor Substrate FamilyJournal of Biological Chemistry, 1997
- Insulin Signalling and Insulin Actions in the Muscles and Livers of Insulin-Resistant, Insulin Receptor Substrate 1-Deficient MiceMolecular and Cellular Biology, 1996
- Insulin Signal Transduction and the IRS ProteinsAnnual Review of Pharmacology and Toxicology, 1996
- Role of IRS-2 in insulin and cytokine signallingNature, 1995
- Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 geneNature, 1994
- Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1Nature, 1994
- Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction proteinNature, 1991