A Convenient Synthesis of 5-Substituted 2-Pyrrolidinones via 2H-Pyran-3(6H)-ones

Abstract
Jones oxidation of 6-hydroxy-2H-pyran-3(6H)-ones, subsequent hydrogenation, oxime formation and catalytic hydrogenation constitute an efficient route for the synthesis of various 5-substituted 2-pyrrolidinone derivatives starting from aldehydes or ketones.

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