Feasibility of MDCT Colonography in Ultra-Low-Dose Technique in the Detection of Colorectal Lesions: Comparison with High-Resolution Video Colonoscopy

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Abstract
OBJECTIVE. The purpose of this study was to assess the feasibility of MDCT colonography in an ultra-low-dose technique in the detection of endoluminal colonic lesions compared with high-resolution video colonoscopy.SUBJECTS AND METHODS. After standard bowel cleansing, 137 patients (77 men, 60 women; mean [± SD] age, 57.1 ± 11.3 years) underwent high-resolution video colonoscopy within 2 hr after ultra-low-dose MDCT colonography had been performed. Ultra-low-dose MDCT colonography was performed with patients in the supine position only using 10 mAs (effective weighted CT dose index, 0.94 mGy). After mathematic noise reduction by nonlinear gaussian filter chains, using dedicated software (ECCET), images were analyzed by two blinded observers in simultaneously displayed interactive 2D and 3D modes. Findings of ultra-low-dose MDCT colonography were compared with the results obtained with high-resolution video colonoscopy.RESULTS. Calculated effective doses were 0.7 and 1.2 mSv for men and women, respectively....

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