Anterior horn cell dysfunction in Alzheimer's disease.
Open Access
- 1 April 1982
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 45 (4) , 378-381
- https://doi.org/10.1136/jnnp.45.4.378
Abstract
Electrophysiological studies were undertaken on 29 patients with Alzheimer's Disease. A reduction in the number of functioning motor units was found in the extensor digitorum brevis muscle. The electrophysiological parameters of the motor unit potentials were increased compared to control values. Four of seven muscle biopsies showed abnormalities ranging from mild to severe. The results suggest dysfunction in the lower motor neurone in this disease.This publication has 10 references indexed in Scilit:
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