TRABECULAR CARCINOMA OF THE SKIN - FURTHER CLINICOPATHOLOGIC AND MORPHOLOGIC STUDY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 106  (8) , 404-408
Abstract
The clinical aspects of 30 cases of trabecular carcinoma of the skin were studied. Twenty-three patients were followed up for > 1 yr. Trabecular carcinoma of the skin is often misdiagnosed as a metastatic malignant tumor. The average age at the time of diagnosis was 68 yr; most tumors occurred during the 7th and 8th decades of life. Most initial lesions were located in the head, neck and upper extremities. Lymph node metastases developed in 13 patients, 3 of whom eventually died of the disease. Local recurrence developed in 10 patients, 4 of whom died of metastatic trabecular carcinoma. The overall mortality was 5 of the 30 patients. Three of the patients in whom generalized metastases developed also suffered from some other severe systemic disorder. Nearly half of the 23 patients are free of disease. Sweat gland differentiation was observed in 2 cases, which indicates that the cell of origin is a multipotential unit capable of both neuroendocrine and sudoriferous differentiation.

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