Halocins: salt-dependent bacteriocins produced by extremely halophilic rods

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Abstract
Strains of halophilic rods, presumably halobacteria, produce substances that inhibit the growth of other halobacteria but not halococci or moderate halophiles. The spectrum of action of these substances, called halocins, was determined on 39 halobacteria or presumed halobacteria. The properties of halocin H4, produced by strain R-4, were studied using Halobacterium halobium as an indicator organism. Halocin H4 is adsorbed by the indicator organism and caused death and lysis. It is a high MW substance(s), destroyed by heat or exposure to low salt concentrations or treatment with a protease. Experiments are presented to show that is not a virus.

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