Further Studies on Nutritional Requirements of the Cotton Rat. (Sigmodon hispidus hispidus).

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Abstract
The cotton rat (S. h. hispidus) was shown not to require a dietary source of biotin or pteroylglutamic acid for optimum growth when a purified ration was fed. The growth response obtained with nicotinic acid supplementation was dependent on the casein (tryptophan) content of the diet in that as the casein level was increased the growth response attributable to the addition of nicotinic acid was decreased. A poor reproduction performance was observed when purified diets were fed. Improvement was noted when liver extract was fed in addition to the purified diet or when stock ration was fed.
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