Causal influences in haematemesis and melaena
Open Access
- 1 February 1965
- Vol. 6 (1) , 1-13
- https://doi.org/10.1136/gut.6.1.1
Abstract
Aspirin causes an erosive gastritis in some but not all patients. Increased acid and pepsin secretion is associated with family inheritance, the blood group and the ABH salivary secretion, and predisposes to bleeding after aspirin. In 321 cases, hereditary effects are minor in comparison with strong extrinsic influences including excessive emotion, fatigue, anxiety, infection, alcohol, irregular meals and heavy smoking. When these destructive influences are conjoined, intensification of 1 or more may precipitate a hemorrhagic "explosion" without the triggering influence of salicylates.Keywords
This publication has 44 references indexed in Scilit:
- Hereditary Aspects of Duodenal Ulceration: Serum-pepsinogen Level in Relation to ABO Blood Groups and Salivary ABH Secretor StatusBMJ, 1964
- ABO Blood Groups of Siblings of Gastric Ulcer and Gastric Carcinoma PatientsBMJ, 1961
- Myocardial Infarction in Patients Treated with Sippy and Other High-Milk DietsCirculation, 1960
- A Review of 300 Patients with Haematemesis or MelaenaBMJ, 1959
- GASTRIC ULCER IN ASSOCIATION WITH HIATAL HERNIAThe Lancet, 1958
- Blood Groups and Susceptibility to DiseaseJournal of Epidemiology and Community Health, 1957
- THE RELATIONSHIP OF CHRONIC PEPTIC ULCER TO CORONARY THROMBOSISThe Lancet Healthy Longevity, 1952
- THE SEPARATE INHERITANCE OF GASTRIC AND DUODENAL ULCERSAnnals of Eugenics, 1951
- The association of gall bladder disease and of peptic ulcer with coronary disease; A post-mortem studyAmerican Heart Journal, 1941
- HqMATEMESIS AND THE WARThe Lancet, 1940